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TitleLARP4A recognizes polyA RNA via a novel binding mechanism mediated by disordered regions and involving the PAM2w motif, revealing interplay between PABP, LARP4A and mRNA.
Journal, issue, pagesNucleic Acids Res., Vol. 47, Page 4272-4291, Year 2019
Publish dateNov 22, 2018 (structure data deposition date)
AuthorsCruz-Gallardo, I. / Martino, L. / Kelly, G. / Atkinson, R.A. / Trotta, R. / De Tito, S. / Coleman, P. / Ahdash, Z. / Gu, Y. / Bui, T.T.T. / Conte, M.R.
External linksNucleic Acids Res. / PubMed:30820564
MethodsNMR (solution)
Structure data

PDB-6i9b:
NMR structure of the La module from human LARP4A
Method: SOLUTION NMR

Source
  • homo sapiens (human)
KeywordsRNA BINDING PROTEIN / La-related proteins / LARPs / PABP-binding protein / La module

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