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TitleCrystal Structure of the first bromodomain of BRD4 in complex with RT56
Journal, issue, pagesTo Be Published
Publish dateNov 19, 2018 (structure data deposition date)
AuthorsPicaud, S. / Traquete, R. / Bernardes, G.J.L. / Newman, J. / Arrowsmith, C.H. / Edwards, A.M. / Bountra, C. / Filippakopoulos, P. / Structural Genomics Consortium (SGC)
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1 Å
Structure data

PDB-6i7y:
Crystal Structure of the first bromodomain of BRD4 in complex with RT56
Method: X-RAY DIFFRACTION / Resolution: 1 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-H7E:
[1-[4-[2-[(4~{S})-6-(4-chlorophenyl)-8-methoxy-1-methyl-4~{H}-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-4-yl]ethanoylamino]phenyl]piperidin-4-yl]-trimethyl-azanium

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / BET / Bromodomain / RT56 / inhibitor / Structural Genomics / Structural Genomics Consortium / SGC

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