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Structure paper

TitleStructure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition.
Journal, issue, pagesIucrj, Vol. 6, Page 317-330, Year 2019
Publish dateSep 22, 2018 (structure data deposition date)
AuthorsCuppari, A. / Korschgen, H. / Fahrenkamp, D. / Schmitz, C. / Guevara, T. / Karmilin, K. / Kuske, M. / Olf, M. / Dietzel, E. / Yiallouros, I. ...Cuppari, A. / Korschgen, H. / Fahrenkamp, D. / Schmitz, C. / Guevara, T. / Karmilin, K. / Kuske, M. / Olf, M. / Dietzel, E. / Yiallouros, I. / de Sanctis, D. / Goulas, T. / Weiskirchen, R. / Jahnen-Dechent, W. / Floehr, J. / Stoecker, W. / Jovine, L. / Gomis-Ruth, F.X.
External linksIucrj / PubMed:30867929
MethodsX-ray diffraction
Resolution2.3 - 3.1 Å
Structure data

PDB-6hpv:
Crystal structure of mouse fetuin-B
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-6ht9:
Mouse fetuin-B in complex with crayfish astacin
Method: X-RAY DIFFRACTION / Resolution: 3.1 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

ChemComp-ZN:
Unknown entry

ChemComp-GOL:
GLYCEROL

Source
  • mus musculus (house mouse)
  • astacus astacus (noble crayfish)
Keywordshydrolase inhibitor / Glycoprotein / cystatin domain / fertilization / egg coat / zona pellucida / hardening / metalloprotease inhibitor / ovastacin / ZP2 / liver-secreted protein / HYDROLASE / peptidase inhibitor / metallopeptidase / astacin / ovastacin inhibitor / fetuin / cystatin

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