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TitlePolysialic acid is a cellular receptor for human adenovirus 52.
Journal, issue, pagesProc. Natl. Acad. Sci. U.S.A., Vol. 115, Page E4264-E4273, Year 2018
Publish dateMar 26, 2018 (structure data deposition date)
AuthorsLenman, A. / Liaci, A.M. / Liu, Y. / Frangsmyr, L. / Frank, M. / Blaum, B.S. / Chai, W. / Podgorski, I.I. / Harrach, B. / Benko, M. ...Lenman, A. / Liaci, A.M. / Liu, Y. / Frangsmyr, L. / Frank, M. / Blaum, B.S. / Chai, W. / Podgorski, I.I. / Harrach, B. / Benko, M. / Feizi, T. / Stehle, T. / Arnberg, N.
External linksProc. Natl. Acad. Sci. U.S.A. / PubMed:29674446
MethodsX-ray diffraction
Resolution1.497 Å
Structure data

PDB-6g47:
Crystal Structure of Human Adenovirus 52 Short Fiber Knob in Complex with alpha-(2,8)-Trisialic Acid (DP3)
Method: X-RAY DIFFRACTION / Resolution: 1.497 Å

Chemicals

ChemComp-SIA:
N-acetyl-alpha-neuraminic acid

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-MRD:
(4R)-2-METHYLPENTANE-2,4-DIOL / precipitant*YM

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • human adenovirus 52
KeywordsCELL ADHESION / polysialic acid / adenovirus / virolectin / fiber knob / cell attachment / viral entry / carbohydrate

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