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-Structure paper
Title | Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation. |
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Journal, issue, pages | Science, Vol. 362, Page 834-839, Year 2018 |
Publish date | Mar 26, 2018 (structure data deposition date) |
Authors | Visnes, T. / Cazares-Korner, A. / Hao, W. / Wallner, O. / Masuyer, G. / Loseva, O. / Mortusewicz, O. / Wiita, E. / Sarno, A. / Manoilov, A. ...Visnes, T. / Cazares-Korner, A. / Hao, W. / Wallner, O. / Masuyer, G. / Loseva, O. / Mortusewicz, O. / Wiita, E. / Sarno, A. / Manoilov, A. / Astorga-Wells, J. / Jemth, A.S. / Pan, L. / Sanjiv, K. / Karsten, S. / Gokturk, C. / Grube, M. / Homan, E.J. / Hanna, B.M.F. / Paulin, C.B.J. / Pham, T. / Rasti, A. / Berglund, U.W. / von Nicolai, C. / Benitez-Buelga, C. / Koolmeister, T. / Ivanic, D. / Iliev, P. / Scobie, M. / Krokan, H.E. / Baranczewski, P. / Artursson, P. / Altun, M. / Jensen, A.J. / Kalderen, C. / Ba, X. / Zubarev, R.A. / Stenmark, P. / Boldogh, I. / Helleday, T. |
External links | Science / PubMed:30442810 |
Methods | X-ray diffraction |
Resolution | 2.1 - 2.51 Å |
Structure data | PDB-6g3x: PDB-6g3y: |
Chemicals | ChemComp-NI: ChemComp-HOH: ChemComp-ELB: ChemComp-ACT: |
Source |
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Keywords | DNA BINDING PROTEIN / N-glycosylase / DNA lyase |