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-Structure paper
Title | Mutational and structural studies uncover crucial amino acids determining activity and stability of 17 beta-HSD14. |
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Journal, issue, pages | J. Steroid Biochem. Mol. Biol., Vol. 189, Page 135-144, Year 2019 |
Publish date | Jan 5, 2018 (structure data deposition date) |
![]() | Badran, M.J. / Bertoletti, N. / Keils, A. / Heine, A. / Klebe, G. / Marchais-Oberwinkler, S. |
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Methods | X-ray diffraction |
Resolution | 1.65 - 1.68 Å |
Structure data | ![]() PDB-6ffb: ![]() PDB-6hno: ![]() PDB-6qck: |
Chemicals | ![]() ChemComp-NAD: ![]() ChemComp-NA: ![]() ChemComp-BGC: ![]() ChemComp-F45: ![]() ChemComp-HOH: ![]() ChemComp-DMS: ![]() ChemComp-HWK: |
Source |
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![]() | OXIDOREDUCTASE / 17b-HSD14 / mutation / inhibition / fragments / soaking |