Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Adventures in Scaffold Morphing: Discovery of Fused Ring Heterocyclic Checkpoint Kinase 1 (CHK1) Inhibitors.
Journal, issue, pages	J. Med. Chem., Vol. 61, Page 1061-1073, Year 2018
Publish date	Dec 20, 2017 (structure data deposition date)
Authors	Yang, B. / Vasbinder, M.M. / Hird, A.W. / Su, Q. / Wang, H. / Yu, Y. / Toader, D. / Lyne, P.D. / Read, J.A. / Breed, J. ...Yang, B. / Vasbinder, M.M. / Hird, A.W. / Su, Q. / Wang, H. / Yu, Y. / Toader, D. / Lyne, P.D. / Read, J.A. / Breed, J. / Ioannidis, S. / Deng, C. / Grondine, M. / DeGrace, N. / Whitston, D. / Brassil, P. / Janetka, J.W.
External links	J. Med. Chem. / PubMed:29301085
Methods	X-ray diffraction
Resolution	1.61 - 1.9 Å
Structure data	PDB-6fc8: CHK1 KINASE IN COMPLEX WITH COMPOUND 13 Method: X-RAY DIFFRACTION / Resolution: 1.61 Å PDB-6fcf: CHK1 KINASE IN COMPLEX WITH COMPOUND 44 Method: X-RAY DIFFRACTION / Resolution: 1.85 Å PDB-6fck: CHK1 KINASE IN COMPLEX WITH COMPOUND 13 Method: X-RAY DIFFRACTION / Resolution: 1.9 Å
Chemicals	ChemComp-SO4: SULFATE ION ChemComp-D4Q: 2-(3-fluorophenyl)-4-[[(3~{S})-piperidin-3-yl]amino]thieno[3,2-c]pyridine-7-carboxamide ChemComp-HOH: WATER ChemComp-D58: 4-[[(2~{R},3~{S})-2-methylpiperidin-3-yl]amino]-2-phenyl-thieno[3,2-c]pyridine-7-carboxamide ChemComp-D4Z: 2-phenyl-4-[[(3~{S})-piperidin-3-yl]amino]-1~{H}-indole-7-carboxamide
Source	homo sapiens (human)
Keywords	TRANSFERASE / INHIBITOR / COMPLEX / CHK1 / KINASE