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TitleDe Novo Design of Selective Quadruplex-Duplex Junction Ligands and Structural Characterisation of Their Binding Mode: Targeting the G4 Hot-Spot.
Journal, issue, pagesChemistry, Year 2020
Publish dateDec 20, 2017 (structure data deposition date)
AuthorsDiaz-Casado, L. / Serrano-Chacon, I. / Montalvillo-Jimenez, L. / Corzana, F. / Bastida, A. / Santana, A.G. / Gonzalez, C. / Asensio, J.L.
External linksChemistry / PubMed:33368678
MethodsNMR (solution)
Structure data

PDB-6fc9:
The 1,8-bis(aminomethyl)anthracene and Quadruplex-duplex junction complex
Method: SOLUTION NMR

Chemicals

ChemComp-D5B:
[8-(azaniumylmethyl)anthracen-1-yl]methylazanium

Source
  • synthetic construct (others)
KeywordsDNA / Quadruplex / Junction / non canonical DNA strucute / ligand-DNA complex

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