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TitlePreclinical safety and efficacy studies with an affinity-enhanced epithelial junction opener and PEGylated liposomal doxorubicin.
Journal, issue, pagesMol Ther Methods Clin Dev, Vol. 2, Page 15005-15005, Year 2015
Publish dateNov 17, 2014 (structure data deposition date)
AuthorsRichter, M. / Yumul, R. / Wang, H. / Saydaminova, K. / Ho, M. / May, D. / Baldessari, A. / Gough, M. / Drescher, C. / Urban, N. ...Richter, M. / Yumul, R. / Wang, H. / Saydaminova, K. / Ho, M. / May, D. / Baldessari, A. / Gough, M. / Drescher, C. / Urban, N. / Roffler, S. / Zubieta, C. / Carter, D. / Fender, P. / Lieber, A.
External linksMol Ther Methods Clin Dev / PubMed:26029716
MethodsX-ray diffraction
Resolution1.49 - 2.65 Å
Structure data

PDB-4wyj:
Adenovirus 3 head domain mutant V239D
Method: X-RAY DIFFRACTION / Resolution: 2.65 Å

PDB-6f6o:
Structure of Adenovirus 3 fiber head V239D mutant
Method: X-RAY DIFFRACTION / Resolution: 1.49 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-HOH:
WATER

Source
  • human adenovirus b serotype 3
KeywordsVIRAL PROTEIN / adenovirus head domain / adenovirus 3 fiber head / capsid protein / cell adhesion

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