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-Structure paper
Title | Crystal structures of thrombin in complex with chemically modified thrombin DNA aptamers reveal the origins of enhanced affinity. |
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Journal, issue, pages | Nucleic Acids Res., Vol. 46, Page 4819-4830, Year 2018 |
Publish date | Oct 9, 2017 (structure data deposition date) |
![]() | Dolot, R. / Lam, C.H. / Sierant, M. / Zhao, Q. / Liu, F.W. / Nawrot, B. / Egli, M. / Yang, X. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.69 - 2.24 Å |
Structure data | ![]() PDB-6eo6: ![]() PDB-6eo7: |
Chemicals | ![]() ChemComp-K: ![]() ChemComp-0G6: ![]() ChemComp-NA: ![]() ChemComp-NAG: ![]() ChemComp-HOH: |
Source |
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![]() | Hydrolase/DNA / alpha thrombin / aptamer / thrombin-mTBA / complex / HYDROLASE-DNA complex / HYDROLASE |