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-Structure paper
Title | Developing and Evaluating Inhibitors against the RNase H Active Site of HIV-1 Reverse Transcriptase. |
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Journal, issue, pages | J. Virol., Vol. 92, Year 2018 |
Publish date | Sep 29, 2017 (structure data deposition date) |
Authors | Boyer, P.L. / Smith, S.J. / Zhao, X.Z. / Das, K. / Gruber, K. / Arnold, E. / Burke, T.R. / Hughes, S.H. |
External links | J. Virol. / PubMed:29643235 |
Methods | X-ray diffraction |
Resolution | 2.2 Å |
Structure data | PDB-6eli: |
Chemicals | ChemComp-T27: ChemComp-BA5: ChemComp-MG: ChemComp-SO4: ChemComp-EDO: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE / P51/P66 / HETERO DIMER / NNRTI / ribonuclease H INHIBITOR / NONNUCLEOSIDE INHIBITOR / AIDS / HIV / R278474 / DIARYLPYRIMIDINE / DAPY / DNA RECOMBINATION / DNA POLYMERASE / ENDONUCLEASE / MULTIFUNCTIONAL / ENZYME / TRANSFERASE / HYDROLASE-INHIBITOR COMPLEX |