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Structure paper

TitleCrystal Structure of a 1,2,4-Triazole Allosteric RNase H Inhibitor in Complex with HIV Reverse Transcriptase
Journal, issue, pagesTo be published
Publish dateAug 8, 2018 (structure data deposition date)
AuthorsKirby, K.A. / Sarafianos, S.G.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.385 Å
Structure data

PDB-6ecl:
Crystal Structure of a 1,2,4-Triazole Allosteric RNase H Inhibitor in Complex with HIV Reverse Transcriptase
Method: X-RAY DIFFRACTION / Resolution: 2.385 Å

Chemicals

ChemComp-MN:
Unknown entry

ChemComp-T90:
1-[4-methoxy-3-[[5-methyl-4-(phenylmethyl)-1,2,4-triazol-3-yl]sulfanylmethyl]phenyl]ethanone

ChemComp-HOH:
WATER

Source
  • human immunodeficiency virus type 1 group m subtype b (isolate bh10)
KeywordsTRANSFERASE / HIV-1 / REVERSE TRANSCRIPTASE / RNASE H / INHIBITOR

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