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Structure paper

TitleCrystal structure of human ER aminopeptidase 1 bound to aryl sulfonamide inhibitor.
Journal, issue, pagesTo Be Published
Publish dateAug 2, 2018 (structure data deposition date)
AuthorsMaben, Z. / Stern, L.J.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.45 Å
Structure data

PDB-6ea4:
ERAP2 bound to Aryl Sulfonamide Uncompetitive Inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MES:
2-(N-MORPHOLINO)-ETHANESULFONIC ACID / pH buffer*YM

ChemComp-J2G:
4-methoxy-3-{[2-(piperidin-1-yl)-4-(trifluoromethyl)phenyl]sulfamoyl}benzoic acid

ChemComp-LYS:
LYSINE

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-IMD:
IMIDAZOLE

ChemComp-PGE:
TRIETHYLENE GLYCOL

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE/INHIBITOR / Inhibitor / Immunity / Aminopeptidase / HYDROLASE / HYDROLASE-INHIBITOR complex

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