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Structure paper

TitleStructural investigation of human S. aureus-targeting antibodies that bind wall teichoic acid.
Journal, issue, pagesMAbs, Vol. 10, Page 979-991, Year 2018
Publish dateJun 26, 2018 (structure data deposition date)
AuthorsFong, R. / Kajihara, K. / Chen, M. / Hotzel, I. / Mariathasan, S. / Hazenbos, W.L.W. / Lupardus, P.J.
External linksMAbs / PubMed:30102105
MethodsX-ray diffraction
Resolution1.7 - 2.39 Å
Structure data

PDB-6dw2:
Structure of the 6078 Antibody Fab fragment bound to a Staphylococcus aureus wall techoic acid analog
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-6dwa:
Structure of the 4497 Antibody Fab fragment bound to a Staphylococcus aureus wall techoic acid analog
Method: X-RAY DIFFRACTION / Resolution: 1.922 Å

PDB-6dwc:
Structure of the apo 4497 antibody Fab fragment
Method: X-RAY DIFFRACTION / Resolution: 2.27 Å

PDB-6dwi:
Structure of the 4462 Antibody Fab fragment bound to a Staphylococcus aureus wall techoic acid analog
Method: X-RAY DIFFRACTION / Resolution: 2.39 Å

Chemicals

ChemComp-NA:
Unknown entry

ChemComp-MLA:
MALONIC ACID

ChemComp-HD4:
4-O-[2-acetamido-2-deoxy-beta-D-glucopyranosyl]-1-O-phosphono-D-ribitol

ChemComp-HOH:
WATER

ChemComp-ACT:
ACETATE ION

ChemComp-GOL:
GLYCEROL

ChemComp-CL:
Unknown entry

ChemComp-FLC:
CITRATE ANION

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Antibody / Fab / wall teichoic acid / WTA / Staphylococcus aureus

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