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-Structure paper
Title | Structure-based Engineering of Reversible Covalent Inhibitors Against Histone Lysine Demethylase 5A |
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Journal, issue, pages | To Be Published |
Publish date | Jun 10, 2018 (structure data deposition date) |
![]() | Horton, J.R. / Liu, X. / Woodcock, C.B. / Shanks, J. / Zhang, X. / Rai, G. / Mott, B. / Jansen, D.J. / Kales, S. / Henderson, M.J. ...Horton, J.R. / Liu, X. / Woodcock, C.B. / Shanks, J. / Zhang, X. / Rai, G. / Mott, B. / Jansen, D.J. / Kales, S. / Henderson, M.J. / Pohida, K. / Fang, Y. / Hu, X. / Jadhav, A. / Maloney, D. / Hall, M.D. / Simeonov, A. / Fu, H. / Vertino, P.M. / Cheng, X. |
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Methods | X-ray diffraction |
Resolution | 1.852 Å |
Structure data | ![]() PDB-6dq7: |
Chemicals | ![]() ChemComp-H6M: ![]() ChemComp-MN: ![]() ChemComp-EDO: ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE/INHIBITOR / DEMETHYLASE INHIBITION / OXIDOREDUCTASE-INHIBITOR complex |