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Title | A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent. |
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Journal, issue, pages | ACS Chem. Biol., Vol. 13, Page 2930-2938, Year 2018 |
Publish date | Jun 6, 2018 (structure data deposition date) |
Authors | Sadek, M.M. / Barlow, N. / Leung, E.W.W. / Williams-Noonan, B.J. / Yap, B.K. / Shariff, F.M. / Caradoc-Davies, T.T. / Nicholson, S.E. / Chalmers, D.K. / Thompson, P.E. ...Sadek, M.M. / Barlow, N. / Leung, E.W.W. / Williams-Noonan, B.J. / Yap, B.K. / Shariff, F.M. / Caradoc-Davies, T.T. / Nicholson, S.E. / Chalmers, D.K. / Thompson, P.E. / Law, R.H.P. / Norton, R.S. |
External links | ACS Chem. Biol. / PubMed:30226743 |
Methods | X-ray diffraction |
Resolution | 1.4 - 2.4 Å |
Structure data | PDB-6dn5: PDB-6dn6: PDB-6dn7: PDB-6dn8: |
Chemicals | ChemComp-SO4: ChemComp-HOH: ChemComp-CL: ChemComp-ACT: |
Source |
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Keywords | IMMUNE SYSTEM/INHIBITOR / proteasomal degradation / nitric oxide / inhibitor / IMMUNE SYSTEM / IMMUNE SYSTEM-INHIBITOR complex |