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TitleSecond bromodomain of Human BRD2 with a Tetrahydroquinoline analogue
Journal, issue, pagesTo Be Published
Publish dateMay 3, 2018 (structure data deposition date)
AuthorsWhite, S.W. / Yun, M.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.05 Å
Structure data

PDB-6dbc:
Second bromodomain of Human BRD2 with a Tetrahydroquinoline analogue
Method: X-RAY DIFFRACTION / Resolution: 1.05 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-G3J:
1-[(2S,4R)-4-[(2-chlorophenyl)amino]-2-methyl-6-(1H-pyrazol-3-yl)-3,4-dihydroquinolin-1(2H)-yl]ethan-1-one

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTranscription/inhibitor / BET / BRD2 / bromodomain / Inhibitor / Complex / Transcription / Transcription-inhibitor complex

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