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Structure paper

TitleStructural and Dynamic Elucidation of a Non-acid PPARgammaPartial Agonist: SR1988.
Journal, issue, pagesNucl Receptor Res, Vol. 5, Year 2018
Publish dateApr 15, 2018 (structure data deposition date)
AuthorsFrkic, R.L. / Chua, B.S. / Shin, Y. / Pascal, B.D. / Novick, S.J. / Kamenecka, T.M. / Griffin, P.R. / Bruning, J.B.
External linksNucl Receptor Res / PubMed:30906767
MethodsX-ray diffraction
Resolution2.395 Å
Structure data

PDB-6d3e:
PPARg LBD in Complex with SR1988
Method: X-RAY DIFFRACTION / Resolution: 2.395 Å

Chemicals

ChemComp-FT7:
1-[(2,4-difluorophenyl)methyl]-2,3-dimethyl-N-[(1R)-1-phenylpropyl]-1H-indole-5-carboxamide

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / type 2 diabetes / nuclear receptor / drug discovery

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