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-Structure paper
Title | Novel Central Nervous System (CNS)-Targeting Protease Inhibitors for Drug-Resistant HIV Infection and HIV-Associated CNS Complications. |
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Journal, issue, pages | Antimicrob. Agents Chemother., Vol. 63, Year 2019 |
Publish date | Apr 10, 2018 (structure data deposition date) |
![]() | Amano, M. / Salcedo-Gomez, P.M. / Yedidi, R.S. / Zhao, R. / Hayashi, H. / Hasegawa, K. / Nakamura, T. / Martyr, C.D. / Ghosh, A.K. / Mitsuya, H. |
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Methods | X-ray diffraction |
Resolution | 1.85 - 1.95 Å |
Structure data | ![]() PDB-6d0d: ![]() PDB-6d0e: |
Chemicals | ![]() ChemComp-FQ4: ![]() ChemComp-HOH: ![]() ChemComp-FQ1: |
Source |
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![]() | HYDROLASE/INHIBITOR / HIV-1 protease / protease inhibitor / darunavir / fluorophenyl / nonpeptidic / TMC-126 / HYDROLASE / HYDROLASE-INHIBITOR complex / difluorophenyl |