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Structure paper

TitleCrystal structure of PT1940 bound to HIF2a-B*:ARNT-B* complex
Journal, issue, pagesTo Be Published
Publish dateApr 9, 2018 (structure data deposition date)
AuthorsDu, X.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.5 - 1.85 Å
Structure data

PDB-6czw:
Crystal structure of PT1940 bound to HIF2a-B*:ARNT-B* complex
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

PDB-6d09:
Crystal structure of PT2440 bound to HIF2a-B*:ARNT-B* complex
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

PDB-6d0c:
Crystal structure of HIF2a-B*:ARNT-B* complex
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-FO7:
{2-bromo-3-(3-chloro-5-fluorophenoxy)-6-[(difluoromethyl)sulfonyl]phenyl}methanol

ChemComp-HOH:
WATER

ChemComp-FOJ:
3-{[(3R)-4-(difluoromethyl)-2,2-difluoro-3-hydroxy-1,1-dioxo-2,3-dihydro-1H-1-benzothiophen-5-yl]oxy}-5-fluorobenzonitrile

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / Hif2a / Pas B domain / ARNT / hypoxia inducible factor / EPAS1

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