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TitleUnifying the Aminohexopyranose- and Peptidyl-Nucleoside Antibiotics: Implications for Antibiotic Design
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 132, Page 11426-11429, Year 2020
Publish dateApr 9, 2018 (structure data deposition date)
AuthorsSerrano, C.M. / Kanna Reddy, H.R. / Eiler, D.R. / Koch, M.R. / Tresco, B.I.C. / Barrows, L.R. / VanderLinden, R.T. / Testa, C.A. / Sebahar, P.R. / Looper, R.E.
External linksAngew. Chem. Int. Ed. Engl. / Search PubMed
MethodsX-ray diffraction
Resolution3.14 Å
Structure data

PDB-6czr:
The structure of amicetin bound to the 70S ribosome
Method: X-RAY DIFFRACTION / Resolution: 3.14 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-ARG:
ARGININE

ChemComp-MPD:
(4S)-2-METHYL-2,4-PENTANEDIOL / precipitant*YM

ChemComp-FSD:
amicetin

ChemComp-ZN:
Unknown entry

ChemComp-SF4:
IRON/SULFUR CLUSTER

ChemComp-HOH:
WATER

Source
  • thermus thermophilus hb8 (bacteria)
  • thermus thermophilus (strain hb8 / atcc 27634 / dsm 579) (bacteria)
  • thermus thermophilus (bacteria)
KeywordsRIBOSOME/ANTIBIOTIC / 70S ribosome / amicetin / antibiotic complex / translation / RIBOSOME-ANTIBIOTIC complex

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