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-Structure paper
Title | Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth. |
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Journal, issue, pages | Nature, Vol. 560, Page 253-257, Year 2018 |
Publish date | Oct 11, 2017 (structure data deposition date) |
![]() | Baell, J.B. / Leaver, D.J. / Hermans, S.J. / Kelly, G.L. / Brennan, M.S. / Downer, N.L. / Nguyen, N. / Wichmann, J. / McRae, H.M. / Yang, Y. ...Baell, J.B. / Leaver, D.J. / Hermans, S.J. / Kelly, G.L. / Brennan, M.S. / Downer, N.L. / Nguyen, N. / Wichmann, J. / McRae, H.M. / Yang, Y. / Cleary, B. / Lagiakos, H.R. / Mieruszynski, S. / Pacini, G. / Vanyai, H.K. / Bergamasco, M.I. / May, R.E. / Davey, B.K. / Morgan, K.J. / Sealey, A.J. / Wang, B. / Zamudio, N. / Wilcox, S. / Garnham, A.L. / Sheikh, B.N. / Aubrey, B.J. / Doggett, K. / Chung, M.C. / de Silva, M. / Bentley, J. / Pilling, P. / Hattarki, M. / Dolezal, O. / Dennis, M.L. / Falk, H. / Ren, B. / Charman, S.A. / White, K.L. / Rautela, J. / Newbold, A. / Hawkins, E.D. / Johnstone, R.W. / Huntington, N.D. / Peat, T.S. / Heath, J.K. / Strasser, A. / Parker, M.W. / Smyth, G.K. / Street, I.P. / Monahan, B.J. / Voss, A.K. / Thomas, T. |
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Methods | X-ray diffraction |
Resolution | 1.85003821102 - 2.128 Å |
Structure data | ![]() PDB-6ba2: ![]() PDB-6ba4: ![]() PDB-6ct2: |
Chemicals | ![]() ChemComp-CL: ![]() ChemComp-ZN: ![]() ChemComp-GOL: ![]() ChemComp-NA: ![]() ChemComp-7KM: ![]() ChemComp-HOH: ![]() ChemComp-ACO: ![]() ChemComp-7L1: ![]() ChemComp-FCV: ![]() ChemComp-MG: |
Source |
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![]() | TRANSFERASE / acetyltransferase / inhibitor / complex / MYST / TRANSFERASE/INHIBITOR / lysine acetyltransferases / TRANSFERASE-INHIBITOR complex |