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-Structure paper
Title | Antigen-Induced Allosteric Changes in a Human IgG1 Fc Increase Low-Affinity Fc gamma Receptor Binding. |
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Journal, issue, pages | Structure, Year 2020 |
Publish date | Feb 22, 2018 (structure data deposition date) |
![]() | Orlandi, C. / Deredge, D. / Ray, K. / Gohain, N. / Tolbert, W. / DeVico, A.L. / Wintrode, P. / Pazgier, M. / Lewis, G.K. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.4 - 2.575 Å |
Structure data | ![]() PDB-6chf: ![]() PDB-6cjc: ![]() PDB-6cjx: |
Chemicals | ![]() ChemComp-HOH: ![]() ChemComp-CL: |
Source |
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![]() | IMMUNE SYSTEM / Immunoglobulin / IgG1 / immunoglobulin-like beta sandwich / FC fragment / LALA mutation |