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-Structure paper
Title | Pyruvate dehydrogenase complex deficiency is linked to regulatory loop disorder in the alpha V138M variant of human pyruvate dehydrogenase. |
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Journal, issue, pages | J. Biol. Chem., Vol. 293, Page 13204-13213, Year 2018 |
Publish date | Feb 12, 2018 (structure data deposition date) |
![]() | Whitley, M.J. / Arjunan, P. / Nemeria, N.S. / Korotchkina, L.G. / Park, Y.H. / Patel, M.S. / Jordan, F. / Furey, W. |
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Methods | X-ray diffraction |
Resolution | 2.69 - 2.7 Å |
Structure data | ![]() PDB-6cer: ![]() PDB-6cfo: |
Chemicals | ![]() ChemComp-TPP: ![]() ChemComp-MG: ![]() ChemComp-HOH: ![]() ChemComp-A5X: |
Source |
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![]() | OXIDOREDUCTASE / pyruvate dehydrogenase deficiency / mutation / thiamin diphosphate / metabolism / THIAMIN PYROPHOSPHATE / ACETYL PHOSPHINATE / INHIBITOR / PYRUVATE DEHYDROGENASE |