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-Structure paper
Title | Structure and inhibition mechanism of the catalytic domain of human squalene epoxidase. |
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Journal, issue, pages | Nat Commun, Vol. 10, Page 97-97, Year 2019 |
Publish date | Jan 19, 2018 (structure data deposition date) |
![]() | Padyana, A.K. / Gross, S. / Jin, L. / Cianchetta, G. / Narayanaswamy, R. / Wang, F. / Wang, R. / Fang, C. / Lv, X. / Biller, S.A. ...Padyana, A.K. / Gross, S. / Jin, L. / Cianchetta, G. / Narayanaswamy, R. / Wang, F. / Wang, R. / Fang, C. / Lv, X. / Biller, S.A. / Dang, L. / Mahoney, C.E. / Nagaraja, N. / Pirman, D. / Sui, Z. / Popovici-Muller, J. / Smolen, G.A. |
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Methods | X-ray diffraction |
Resolution | 2.3 - 3 Å |
Structure data | ![]() PDB-6c6n: ![]() PDB-6c6p: ![]() PDB-6c6r: |
Chemicals | ![]() ChemComp-GOL: ![]() ChemComp-SO4: ![]() ChemComp-CPS: ![]() ChemComp-EKV: ![]() ChemComp-FAD: ![]() ChemComp-HOH: ![]() ChemComp-EMV: ![]() ChemComp-PEG: |
Source |
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![]() | FLAVOPROTEIN/INHIBITOR / Cholesterol Synthesis Pathway / SQLE / ERG1 / FAD-dependent Monooxygenase / Squalene hydroxylase / Squalene-2 / 3-epoxidase / FLAVOPROTEIN / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex / FLAVOPROTEIN-INHIBITOR complex / OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / Complex |