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-Structure paper
Title | A small molecule inhibitor of Rheb selectively targets mTORC1 signaling. |
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Journal, issue, pages | Nat Commun, Vol. 9, Page 548-548, Year 2018 |
Publish date | Dec 5, 2017 (structure data deposition date) |
![]() | Mahoney, S.J. / Narayan, S. / Molz, L. / Berstler, L.A. / Kang, S.A. / Vlasuk, G.P. / Saiah, E. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.65 - 2.6 Å |
Structure data | ![]() PDB-5yxh: ![]() PDB-6bsx: ![]() PDB-6bt0: |
Chemicals | ![]() ChemComp-GDP: ![]() ChemComp-MG: ![]() ChemComp-HOH: ![]() ChemComp-ACT: ![]() ChemComp-E7S: ![]() ChemComp-EDO: ![]() ChemComp-E7V: |
Source |
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![]() | SIGNALING PROTEIN / GTPase / mTORC1 signaling / Rheb / mTORC1 G-protein |