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-Structure paper
Title | Structural Basis for Human DNA Polymerase Kappa to Bypass Cisplatin Intrastrand Cross-Link (Pt-GG) Lesion as an Efficient and Accurate Extender. |
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Journal, issue, pages | J. Mol. Biol., Vol. 430, Page 1577-1589, Year 2018 |
Publish date | Dec 1, 2017 (structure data deposition date) |
Authors | Jha, V. / Ling, H. |
External links | J. Mol. Biol. / PubMed:29715472 |
Methods | X-ray diffraction |
Resolution | 2.8 - 3.15 Å |
Structure data | PDB-6brx: PDB-6bs1: |
Chemicals | ChemComp-MG: ChemComp-0KX: ChemComp-PEG: ChemComp-CPT: ChemComp-HOH: ChemComp-IOD: ChemComp-DZ4: |
Source |
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Keywords | REPLICATION / Cisplatin / DNA adduct / translesion DNA synthesis / polymerase kappa / chemoresistance |