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Structure paper

TitleApurinic/apyrimidinic (AP) endonuclease 1 processing of AP sites with 5' mismatches.
Journal, issue, pagesActa Crystallogr D Struct Biol, Vol. 74, Page 760-768, Year 2018
Publish dateNov 20, 2017 (structure data deposition date)
AuthorsFairlamb, M.S. / Whitaker, A.M. / Freudenthal, B.D.
External linksActa Crystallogr D Struct Biol / PubMed:30082511
MethodsX-ray diffraction
Resolution1.59 - 2.538 Å
Structure data

PDB-6boq:
Human APE1 substrate complex with an A/A mismatch adjacent the THF
Method: X-RAY DIFFRACTION / Resolution: 1.96 Å

PDB-6bor:
Human APE1 substrate complex with an G/G mismatch adjacent the THF
Method: X-RAY DIFFRACTION / Resolution: 1.84 Å

PDB-6bos:
Human APE1 substrate complex with an A/C mismatch adjacent the THF
Method: X-RAY DIFFRACTION / Resolution: 2.304 Å

PDB-6bot:
Human APE1 substrate complex with an C/C mismatch adjacent the THF
Method: X-RAY DIFFRACTION / Resolution: 2.3 Å

PDB-6bou:
Human APE1 substrate complex with an T/C mismatch adjacent the THF
Method: X-RAY DIFFRACTION / Resolution: 2.538 Å

PDB-6bov:
Human APE1 substrate complex with an A/G mismatch adjacent the THF
Method: X-RAY DIFFRACTION / Resolution: 1.975 Å

PDB-6bow:
Human APE1 substrate complex with an T/T mismatch adjacent the THF
Method: X-RAY DIFFRACTION / Resolution: 1.59 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

ChemComp-CL:
Unknown entry

ChemComp-PEG:
DI(HYDROXYETHYL)ETHER

Source
  • homo sapiens (human)
  • synthetic construct (others)
KeywordsDNA BINDING PROTEIN/DNA / HYDROLASE LYASE / DNA / DNA BINDING PROTEIN / DNA BINDING PROTEIN-DNA complex / HYDROLASE / LYASE / DNA

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