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-Structure paper
Title | Fluorescent indomethacin-dansyl conjugates utilize the membrane-binding domain of cyclooxygenase-2 to block the opening to the active site. |
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Journal, issue, pages | J. Biol. Chem., Vol. 294, Page 8690-8698, Year 2019 |
Publish date | Nov 9, 2017 (structure data deposition date) |
![]() | Xu, S. / Uddin, M.J. / Banerjee, S. / Duggan, K. / Musee, J. / Kiefer, J.R. / Ghebreselasie, K. / Rouzer, C.A. / Marnett, L.J. |
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Methods | X-ray diffraction |
Resolution | 2.217 - 2.22 Å |
Structure data | ![]() PDB-6bl3: ![]() PDB-6bl4: |
Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-HEM: ![]() ChemComp-L7M: ![]() ChemComp-BOG: ![]() ChemComp-HOH: ![]() ChemComp-DXS: |
Source |
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![]() | OXIDOREDUCTASE/INHIBITOR / cyclooxygenase-2 / fluorescent inhibitor complex / OXIDOREDUCTASE-INHIBITOR complex / protein-inhibitor complex / fluorescent inhibitor / MEMBRANE PROTEIN |