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-Structure paper
Title | Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine-based inhibitor co-crystal structure. |
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Journal, issue, pages | Protein Sci., Vol. 27, Page 672-680, Year 2018 |
Publish date | Nov 6, 2017 (structure data deposition date) |
Authors | Marcotte, D.J. / Hus, J.C. / Banos, C.C. / Wildes, C. / Arduini, R. / Bergeron, C. / Hession, C.A. / Baker, D.P. / Lin, E. / Guckian, K.M. ...Marcotte, D.J. / Hus, J.C. / Banos, C.C. / Wildes, C. / Arduini, R. / Bergeron, C. / Hession, C.A. / Baker, D.P. / Lin, E. / Guckian, K.M. / Dunah, A.W. / Silvian, L.F. |
External links | Protein Sci. / PubMed:29280296 |
Methods | X-ray diffraction |
Resolution | 1.75 - 2.43 Å |
Structure data | PDB-6bjn: PDB-6bjo: |
Chemicals | ChemComp-HOH: ChemComp-DUY: |
Source |
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Keywords | PEPTIDE BINDING PROTEIN / PICK1 PDZ Domain Class II PDZ binding motif / PICK1 PDZ Domain inhibitor complex Lock and Chop |