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-Structure paper
Title | Imidazo[1,2-a]pyridin-6-yl-benzamide analogs as potent RAF inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 27, Page 5221-5224, Year 2017 |
Publish date | Jan 30, 2017 (structure data deposition date) |
![]() | Smith, A. / Ni, Z.J. / Poon, D. / Huang, Z. / Chen, Z. / Zhang, Q. / Tandeske, L. / Merritt, H. / Shoemaker, K. / Chan, J. ...Smith, A. / Ni, Z.J. / Poon, D. / Huang, Z. / Chen, Z. / Zhang, Q. / Tandeske, L. / Merritt, H. / Shoemaker, K. / Chan, J. / Kaufman, S. / Huh, K. / Murray, J. / Appleton, B.A. / Cowan-Jacob, S.W. / Scheufler, C. / Kanazawa, T. / Jansen, J.M. / Stuart, D. / Shafer, C.M. |
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Methods | X-ray diffraction |
Resolution | 2.15 - 2.68 Å |
Structure data | ![]() PDB-5mz3: ![]() PDB-6b8u: |
Chemicals | ![]() ChemComp-8EN: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / kinase / inhibitor / phosphotransferase / Transferase/Transferase Inhibitor / Proto-oncogene B-Raf / p94 / v-Raf murine sarcoma viral oncogene homolog B1 / ONCOPROTEIN / Transferase-Transferase Inhibitor complex |