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-Structure paper
Title | Optimized arylomycins are a new class of Gram-negative antibiotics. |
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Journal, issue, pages | Nature, Vol. 561, Page 189-194, Year 2018 |
Publish date | Oct 5, 2017 (structure data deposition date) |
Authors | Smith, P.A. / Koehler, M.F.T. / Girgis, H.S. / Yan, D. / Chen, Y. / Crawford, J.J. / Durk, M.R. / Higuchi, R.I. / Kang, J. / Murray, J. ...Smith, P.A. / Koehler, M.F.T. / Girgis, H.S. / Yan, D. / Chen, Y. / Crawford, J.J. / Durk, M.R. / Higuchi, R.I. / Kang, J. / Murray, J. / Paraselli, P. / Park, S. / Phung, W. / Quinn, J.G. / Roberts, T.C. / Rouge, L. / Schwarz, J.B. / Skippington, E. / Wai, J. / Xu, M. / Yu, Z. / Zhang, H. / Tan, M.W. / Heise, C.E. |
External links | Nature / PubMed:30209367 |
Methods | X-ray diffraction |
Resolution | 2.407 Å |
Structure data | PDB-6b88: |
Chemicals | ChemComp-CZD: ChemComp-1PE: ChemComp-HOH: |
Source |
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Keywords | HYDROLASE/HYDROLASE inhibitor / Signal peptidase / SBDD / antibiotic / HYDROLASE / HYDROLASE-HYDROLASE inhibitor complex |