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-Structure paper
Title | Design and Mechanism of (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent gamma-Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Addiction. |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 140, Page 2151-2164, Year 2018 |
Publish date | Oct 2, 2017 (structure data deposition date) |
![]() | Juncosa, J.I. / Takaya, K. / Le, H.V. / Moschitto, M.J. / Weerawarna, P.M. / Mascarenhas, R. / Liu, D. / Dewey, S.L. / Silverman, R.B. |
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Methods | X-ray diffraction |
Resolution | 1.95 Å |
Structure data | ![]() PDB-6b6g: |
Chemicals | ![]() ChemComp-FES: ![]() ChemComp-RMT: ![]() ChemComp-ACT: ![]() ChemComp-GOL: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / Inactivator / GABA Aminotransferase / PLP |