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-Structure paper
| Title | Discovery of orally efficacious ROR gamma t inverse agonists, part 1: Identification of novel phenylglycinamides as lead scaffolds. |
|---|---|
| Journal, issue, pages | Bioorg. Med. Chem., Vol. 26, Page 483-500, Year 2018 |
| Publish date | Sep 20, 2017 (structure data deposition date) |
Authors | Shirai, J. / Tomata, Y. / Kono, M. / Ochida, A. / Fukase, Y. / Sato, A. / Masada, S. / Kawamoto, T. / Yonemori, K. / Koyama, R. ...Shirai, J. / Tomata, Y. / Kono, M. / Ochida, A. / Fukase, Y. / Sato, A. / Masada, S. / Kawamoto, T. / Yonemori, K. / Koyama, R. / Nakagawa, H. / Nakayama, M. / Uga, K. / Shibata, A. / Koga, K. / Okui, T. / Shirasaki, M. / Skene, R. / Sang, B. / Hoffman, I. / Lane, W. / Fujitani, Y. / Yamasaki, M. / Yamamoto, S. |
External links | Bioorg. Med. Chem. / PubMed:29262987 |
| Methods | X-ray diffraction |
| Resolution | 2.69 Å |
| Structure data | ![]() PDB-6b30: |
| Chemicals | ![]() ChemComp-CFG: ![]() ChemComp-HOH: |
| Source |
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Keywords | SIGNALING PROTEIN / Complex / inverse agonist / Nuclear Hormone Receptor |
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