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-Structure paper
Title | Leveraging Compound Promiscuity to Identify Targetable Cysteines within the Kinome. |
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Journal, issue, pages | Cell Chem Biol, Vol. 26, Page 818-829.e9, Year 2019 |
Publish date | Aug 28, 2017 (structure data deposition date) |
Authors | Rao, S. / Gurbani, D. / Du, G. / Everley, R.A. / Browne, C.M. / Chaikuad, A. / Tan, L. / Schroder, M. / Gondi, S. / Ficarro, S.B. ...Rao, S. / Gurbani, D. / Du, G. / Everley, R.A. / Browne, C.M. / Chaikuad, A. / Tan, L. / Schroder, M. / Gondi, S. / Ficarro, S.B. / Sim, T. / Kim, N.D. / Berberich, M.J. / Knapp, S. / Marto, J.A. / Westover, K.D. / Sorger, P.K. / Gray, N.S. |
External links | Cell Chem Biol / PubMed:30982749 |
Methods | X-ray diffraction |
Resolution | 2.05 - 2.402 Å |
Structure data | PDB-6ate: PDB-6g54: PDB-6ges: |
Chemicals | ChemComp-6H3: ChemComp-HOH: ChemComp-SO4: ChemComp-EDO: ChemComp-CL: ChemComp-EWH: |
Source |
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Keywords | TRANSFERASE/TRANSFERASE INHIBITOR / KINASE / PHOSPHORYLATION / TRANSFERASE-TRANSFERASE INHIBITOR COMPLEX / TRANSFERASE / covalent inhibitor / MAPK / Structural Genomics / Structural Genomics Consortium / SGC |