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Structure paper

TitleStructure of the activated Edc1-Dcp1-Dcp2-Edc3 mRNA decapping complex with substrate analog poised for catalysis.
Journal, issue, pagesNat Commun, Vol. 9, Page 1152-1152, Year 2018
Publish dateAug 8, 2017 (structure data deposition date)
AuthorsMugridge, J.S. / Tibble, R.W. / Ziemniak, M. / Jemielity, J. / Gross, J.D.
External linksNat Commun / PubMed:29559651
MethodsX-ray diffraction
Resolution2.84 Å
Structure data

PDB-6am0:
Crystal structure of K. lactis Edc1-Dcp1-Dcp2-Edc3 decapping complex with synthetic cap substrate analog
Method: X-RAY DIFFRACTION / Resolution: 2.84 Å

Chemicals

ChemComp-MG:
Unknown entry

ChemComp-6VQ:
[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-3~{H}-purin-7-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-sulfanyl-phosphoryl] [[[(2~{R},3~{S},4~{R},5~{R})-5-(2-azanyl-7-methyl-6-oxidanylidene-3~{H}-purin-7-ium-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-sulfanyl-phosphoryl]oxy-oxidanyl-phosphoryl] hydrogen phosphate

Source
  • kluyveromyces lactis (strain atcc 8585 / cbs 2359 / dsm 70799 / nbrc 1267 / nrrl y-1140 / wm37) (yeast)
KeywordsTRANSLATION / mRNA decay / decapping / Nudix / nucleotide analog

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