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Structure paper

TitleA V-to-F substitution in SK2 channels causes Ca2+hypersensitivity and improves locomotion in a C. elegans ALS model.
Journal, issue, pagesSci Rep, Vol. 8, Page 10749-10749, Year 2018
Publish dateAug 7, 2017 (structure data deposition date)
AuthorsNam, Y.W. / Baskoylu, S.N. / Gazgalis, D. / Orfali, R. / Cui, M. / Hart, A.C. / Zhang, M.
External linksSci Rep / PubMed:30013223
MethodsX-ray diffraction
Resolution2.2 - 2.5 Å
Structure data

PDB-6ale:
A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

PDB-6czq:
A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-1KP:
(3E)-6,7-dichloro-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-one

ChemComp-GOL:
GLYCEROL

ChemComp-CA:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
  • rattus norvegicus (Norway rat)
KeywordsMETAL TRANSPORT / Calcium binding protein

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