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-Structure paper
Title | Structural insights into FTO's catalytic mechanism for the demethylation of multiple RNA substrates. |
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Journal, issue, pages | Proc. Natl. Acad. Sci. U.S.A., Vol. 116, Page 2919-2924, Year 2019 |
Publish date | Apr 2, 2018 (structure data deposition date) |
Authors | Zhang, X. / Wei, L.H. / Wang, Y. / Xiao, Y. / Liu, J. / Zhang, W. / Yan, N. / Amu, G. / Tang, X. / Zhang, L. / Jia, G. |
External links | Proc. Natl. Acad. Sci. U.S.A. / PubMed:30718435 |
Methods | X-ray diffraction |
Resolution | 3.3 Å |
Structure data | PDB-5zmd: |
Chemicals | ChemComp-MN: ChemComp-OGA: ChemComp-HOH: |
Source |
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Keywords | OXIDOREDUCTASE/DNA / RNA demetheylase FTO / m6A / substrate preference / RNA BINDING PROTEIN / OXIDOREDUCTASE-DNA complex |