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Structure paper

TitleStructural mechanism of DNA recognition by the p204 HIN domain.
Journal, issue, pagesNucleic Acids Res., Year 2021
Publish dateDec 15, 2017 (structure data deposition date)
AuthorsFan, X. / Jiang, J. / Zhao, D. / Chen, F. / Ma, H. / Smith, P. / Unterholzner, L. / Xiao, T.S. / Jin, T.
External linksNucleic Acids Res. / PubMed:33619523
MethodsX-ray diffraction
Resolution1.581 - 4.5 Å
Structure data

PDB-5yzp:
Crystal structure of p204 HINa domain
Method: X-RAY DIFFRACTION / Resolution: 1.581 Å

PDB-5yzw:
Crystal structure of p204 HINb domain
Method: X-RAY DIFFRACTION / Resolution: 2.001 Å

PDB-5z7d:
p204HINab-dsDNA complex structure
Method: X-RAY DIFFRACTION / Resolution: 4.5 Å

Chemicals

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • mus musculus domesticus (western European house mouse)
  • mus musculus (house mouse)
  • vaccinia virus
KeywordsIMMUNE SYSTEM / DNA sensor / pattern recognition receptors / type I-IFN / PYHIN family / AIM-2 like receptors / Interferon inducible gene 204 / IFI204 / HIN200 superfamily / innate immune receptors

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