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Structure paper

TitleCrystal structures of the gastric proton pump
Journal, issue, pagesNature, Vol. 556, Page 214-218, Year 2018
Publish dateOct 19, 2017 (structure data deposition date)
AuthorsAbe, K. / Irie, K. / Nakanishi, H. / Suzuki, H. / Fujiyoshi, Y.
External linksNature / PubMed:29618813
MethodsX-ray diffraction
Resolution2.79977781895 - 2.79988962319 Å
Structure data

PDB-5ylu:
Crystal structure of the gastric proton pump complexed with vonoprazan
Method: X-RAY DIFFRACTION / Resolution: 2.79988962319 Å

PDB-5ylv:
Crystal structure of the gastric proton pump complexed with SCH28080
Method: X-RAY DIFFRACTION / Resolution: 2.79977781895 Å

Chemicals

ChemComp-HKT:
1-[5-(2-fluorophenyl)-1-pyridin-3-ylsulfonyl-pyrrol-3-yl]-~{N}-methyl-methanamine / medication, antibiotic*YM

ChemComp-PCW:
1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE / DOPC, phospholipid*YM

ChemComp-MG:
Unknown entry

ChemComp-CE1:
O-DODECANYL OCTAETHYLENE GLYCOL

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-HOH:
WATER

ChemComp-8WX:
2-(2-methyl-8-phenylmethoxy-imidazo[1,2-a]pyridin-3-yl)ethanenitrile

ChemComp-RB:
RUBIDIUM ION

Source
  • sus scrofa (pig)
KeywordsMEMBRANE PROTEIN / gastric / proton pump / H+ / K+-ATPase / P-type ATPase / transporter

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