+Search query
-Structure paper
Title | Discovery and structure-activity relationship study of 1,3,6-trisubstituted 1,4-diazepane-7-ones as novel human kallikrein 7 inhibitors |
---|---|
Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 27, Page 5272-5276, Year 2017 |
Publish date | Aug 25, 2017 (structure data deposition date) |
Authors | Murafuji, H. / Sakai, H. / Goto, M. / Imajo, S. / Sugawara, H. / Muto, T. |
External links | Bioorg. Med. Chem. Lett. / PubMed:29102227 |
Methods | X-ray diffraction |
Resolution | 2.15 - 2.4 Å |
Structure data | PDB-5y9l: PDB-5yjk: |
Chemicals | ChemComp-8R3: ChemComp-CL: ChemComp-HOH: ChemComp-8VX: |
Source |
|
Keywords | HYDROLASE / protease / inhibitor complex |