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TitleCrystal Structure of LSD1 in Complex with 4-[5-(Piperidin-4-ylmethoxy)-2-(p-tolyl)pyridin-3-yl]benzonitrile.
Journal, issue, pagesMolecules, Vol. 23, Year 2018
Publish dateOct 10, 2017 (structure data deposition date)
AuthorsNiwa, H. / Sato, S. / Hashimoto, T. / Matsuno, K. / Umehara, T.
External linksMolecules / PubMed:29949906
MethodsX-ray diffraction
Resolution2.96 Å
Structure data

PDB-5yjb:
LSD1-CoREST in complex with 4-[5-(piperidin-4-ylmethoxy)-2-(p-tolyl)pyridin-3-yl]benzonitrile
Method: X-RAY DIFFRACTION / Resolution: 2.96 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-8WC:
4-[2-(4-methylphenyl)-5-(piperidin-4-ylmethoxy)pyridin-3-yl]benzenecarbonitrile

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsOXIDOREDUCTASE/TRANSCRIPTION/INHIBITOR / DEMETHYLASE / AMINE OXIDASE / CHROMATIN / HISTONE / FAD / COREPRESSOR / OXIDOREDUCTASE-TRANSCRIPTION-INHIBITOR complex

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