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IF

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Structure paper

Titleto be published
Journal, issue, pagesto be published
Publish dateSep 22, 2017 (structure data deposition date)
AuthorsChitnumsub, P. / Jaruwat, A.
External linksPubMed:pdb-5yg1
MethodsX-ray diffraction
Resolution2.45 Å
Structure data

PDB-5yg1:
Plasmodium vivax SHMT bound with PLP-glycine and GS704
Method: X-RAY DIFFRACTION / Resolution: 2.45 Å

Chemicals

ChemComp-PLG:
N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE]

ChemComp-8UU:
3-[1-[3-[(4~{S})-6-azanyl-5-cyano-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazol-4-yl]-5-(trifluoromethyl)phenyl]piperidin-4-yl]propanoic acid

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • plasmodium vivax (malaria parasite P. vivax)
KeywordsTRANSFERASE/INHIBITOR / alpha and beta protein / Transferase / methyltransferase activity / Inhibitor / TRANSFERASE-INHIBITOR complex

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