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Structure paper

TitleThe dUTPase of white spot syndrome virus assembles its active sites in a noncanonical manner.
Journal, issue, pagesJ. Biol. Chem., Vol. 293, Page 1088-1099, Year 2018
Publish dateAug 9, 2017 (structure data deposition date)
AuthorsZang, K. / Li, F. / Ma, Q.
External linksJ. Biol. Chem. / PubMed:29187596
MethodsX-ray diffraction
Resolution1.56 - 2.4 Å
Structure data

PDB-5y5o:
Crystal structure of the dUTPase of white spot syndrome virus in the apo state
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-5y5p:
Crystal structure of the dUTPase of white spot syndrome virus in complex with dU,PPi and Mg2+
Method: X-RAY DIFFRACTION / Resolution: 2.03 Å

PDB-5y5q:
Crystal structure of the WSSV dUTPase D88N/R158E mutant in complex with dUTP
Method: X-RAY DIFFRACTION / Resolution: 1.56 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-DUR:
2'-DEOXYURIDINE / antivirus*YM

ChemComp-POP:
PYROPHOSPHATE 2-

ChemComp-MG:
Unknown entry

ChemComp-DUT:
DEOXYURIDINE-5'-TRIPHOSPHATE

Source
  • white spot syndrome virus (isolate shrimp/china/tongan/1996)
KeywordsVIRAL PROTEIN / dUTPase / WSSV / pyrophosphatase / dUTP

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