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TitleCrystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido)- N-hydroxy-4-methylpentanamide.
Journal, issue, pagesTo Be Published
Publish dateJul 19, 2017 (structure data deposition date)
AuthorsMarapaka, A.K. / Addlagatta, A.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.83 Å
Structure data

PDB-5y19:
Crystal structure of Plasmodium falciparum aminopeptidase N in complex with (S)-2-((2S,3R)-3-amino-2-hydroxy-4-phenylbutanamido)- N-hydroxy-4-methylpentanamide.
Method: X-RAY DIFFRACTION / Resolution: 1.83 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MG:
Unknown entry

ChemComp-GOL:
GLYCEROL

ChemComp-8KO:
(2S)-2-[[(2S,3R)-3-azanyl-2-oxidanyl-4-phenyl-butanoyl]amino]-4-methyl-N-oxidanyl-pentanamide

ChemComp-HOH:
WATER

Source
  • plasmodium falciparum (malaria parasite P. falciparum)
KeywordsHYDROLASE/HYDROLASE INHIBITOR / M1-class Aminopeptidase / HYDROLASE / HYDROLASE-HYDROLASE INHIBITOR complex

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