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TitleHeat-induced native dimerization prevents amyloid formation by variable domain from immunoglobulin light-chain REI
Journal, issue, pagesFEBS J., Vol. 284, Page 3114-3127, Year 2017
Publish dateMay 31, 2017 (structure data deposition date)
AuthorsNawata, M. / Tsutsumi, H. / Kobayashi, Y. / Unzai, S. / Mine, S. / Nakamura, T. / Uegaki, K. / Kamikubo, H. / Kataoka, M. / Hamada, D.
External linksFEBS J. / PubMed:28736891
MethodsX-ray diffraction
Resolution2.88 - 2.9 Å
Structure data

PDB-5xp1:
Structure of monomeric mutant of REI immunoglobulin light chain variable domain crystallized at pH 6
Method: X-RAY DIFFRACTION / Resolution: 2.88 Å

PDB-5xqy:
Structure of monomeric mutant of REI immunoglobulin light chain variable domain crystallized at pH 8
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / Immunoglobulin

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