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Structure paper

TitleStructural insights into the committed step of bacterial phospholipid biosynthesis.
Journal, issue, pagesNat Commun, Vol. 8, Page 1691-1691, Year 2017
Publish dateApr 30, 2017 (structure data deposition date)
AuthorsLi, Z. / Tang, Y. / Wu, Y. / Zhao, S. / Bao, J. / Luo, Y. / Li, D.
External linksNat Commun / PubMed:29167463
MethodsX-ray diffraction
Resolution1.481 - 2.41 Å
Structure data

PDB-5xj5:
Crystal structure of PlsY (YgiH), an integral membrane glycerol 3-phosphate acyltransferase - the monoacylglycerol form
Method: X-RAY DIFFRACTION / Resolution: 1.481 Å

PDB-5xj6:
Crystal structure of PlsY (YgiH), an integral membrane glycerol 3-phosphate acyltransferase - the glycerol 3-phosphate form
Method: X-RAY DIFFRACTION / Resolution: 2.37 Å

PDB-5xj7:
Crystal structure of PlsY (YgiH), an integral membrane glycerol 3-phosphate acyltransferase - the acyl phosphate form
Method: X-RAY DIFFRACTION / Resolution: 1.772 Å

PDB-5xj8:
Crystal structure of PlsY (YgiH), an integral membrane glycerol 3-phosphate acyltransferase - the lysphosphatidic acid form
Method: X-RAY DIFFRACTION / Resolution: 2.41 Å

PDB-5xj9:
Crystal structure of PlsY (YgiH), an integral membrane glycerol 3-phosphate acyltransferase - the orthophosphate form
Method: X-RAY DIFFRACTION / Resolution: 1.83 Å

Chemicals

ChemComp-SO4:
SULFATE ION / Sulfate

ChemComp-78M:
(2S)-2,3-DIHYDROXYPROPYL(7Z)-PENTADEC-7-ENOATE

ChemComp-PGE:
TRIETHYLENE GLYCOL / Polyethylene glycol

ChemComp-GLY:
GLYCINE / Glycine

ChemComp-HOH:
WATER / Water

ChemComp-G3P:
SN-GLYCEROL-3-PHOSPHATE / Glycerol 3-phosphate

ChemComp-OLC:
(2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate

ChemComp-PO4:
PHOSPHATE ION / Phosphate

ChemComp-87O:
phosphono hexadecanoate

ChemComp-K:
Unknown entry

ChemComp-NKO:
(2R)-2-hydroxy-3-(phosphonooxy)propyl hexadecanoate

Source
  • aquifex aeolicus (bacteria)
KeywordsTRANSFERASE / glycerol 3-phosphate acyltransferase / glycerylphosphate acyltransferase / GPAT / in meso / lipid cubic phase / lipidic cubic phase / lipid metabolism / monoacylglycerol / phospholipid biosynthesis / PlsY / YgiH / substrate / 16:0-P / acylP / acyl phosphate / palmitoyl phosphate / 1-hexadecanoyl-sn-glycero-3-phosphate / 1-palmitoyl-2-hydroxy-sn-glycero-3-phosphate / LPA / lysophophatidic acid / lyso PA / lysoPA / 16:0 lyso PA / palmitoyl lysophosphatidic acid / PA(16:0/0:0) / phosphate / product

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