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Structure paper

TitleStructure of macrophage migration inhibitory factor in complex with methotrexate.
Journal, issue, pagesActa Crystallogr D Struct Biol, Vol. 77, Page 293-299, Year 2021
Publish dateApr 5, 2017 (structure data deposition date)
AuthorsFukushima, K. / Furuya, M. / Kamimura, T. / Takimoto-Kamimura, M.
External linksActa Crystallogr D Struct Biol / PubMed:33645533
MethodsX-ray diffraction
Resolution2.5 Å
Structure data

PDB-5xej:
Crystal Structure of Macrophage Migration Inhibitory Factor bound to MTX
Method: X-RAY DIFFRACTION / Resolution: 2.5 Å

Chemicals

ChemComp-SO4:
SULFATE ION

ChemComp-6UV:
(2~{R})-2-[[4-[[2,4-bis(azanyl)pteridin-6-yl]methyl-methyl-amino]phenyl]carbonylamino]pentanedioic acid

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsISOMERASE/INHIBITOR / ISOMERASE-INHIBITOR complex

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