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TitleNa+-mimicking ligands stabilize the inactive state of leukotriene B4receptor BLT1.
Journal, issue, pagesNat. Chem. Biol., Vol. 14, Page 262-269, Year 2018
Publish dateFeb 3, 2017 (structure data deposition date)
AuthorsHori, T. / Okuno, T. / Hirata, K. / Yamashita, K. / Kawano, Y. / Yamamoto, M. / Hato, M. / Nakamura, M. / Shimizu, T. / Yokomizo, T. ...Hori, T. / Okuno, T. / Hirata, K. / Yamashita, K. / Kawano, Y. / Yamamoto, M. / Hato, M. / Nakamura, M. / Shimizu, T. / Yokomizo, T. / Miyano, M. / Yokoyama, S.
External linksNat. Chem. Biol. / PubMed:29309055
MethodsX-ray diffraction
Resolution3.7 Å
Structure data

PDB-5x33:
Leukotriene B4 receptor BLT1 in complex with BIIL260
Method: X-RAY DIFFRACTION / Resolution: 3.7 Å

Chemicals

ChemComp-7Y9:
4-[[3-[[4-[2-(4-hydroxyphenyl)propan-2-yl]phenoxy]methyl]phenyl]methoxy]benzenecarboximidamide

Source
  • cavia porcellus (domestic guinea pig)
  • enterobacteria phage rb55 (virus)
KeywordsMEMBRANE PROTEIN / helix

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