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TitleStructure of human PARP1 catalytic domain bound to a phthalazinone inhibitor
Journal, issue, pagesTo Be Published
Publish dateDec 4, 2016 (structure data deposition date)
AuthorsCao, R. / Wang, Y.L. / Zhou, J. / Huang, N. / Xu, B.L.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-5wrz:
Structure of human PARP1 catalytic domain bound to a phthalazinone inhibitor
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-7U3:
7-fluoranyl-4-[[(3R)-pyrrolidin-3-yl]methoxy]-2H-phthalazin-1-one

Source
  • homo sapiens (human)
KeywordsTRANSFERASE/TRANSFERASE INHIBITOR / Inhibitor / Complex / TRANSFERASE-TRANSFERASE INHIBITOR complex

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